Neuroanatomy of dyslexia

Ramus, F.

CNRS

Dyslexia is a neurodevelopmental disorder under genetic influence, affecting 3-7% of school-age population. It is characterized by a severe difficulty in reading acquisition despite normal intelligence, education, and sensory functions. Understanding the links between genetic variations, brain disruptions, and specific cognitive impairments remains an important challenge for research on dyslexia. To this end, finely characterizing potential neuroanatomical markers of the disorder appears essential. This talk will review my team?s recent attempts to understand in what respect the brains of dyslexic individuals differ from those of control participants. I will review our recent research on the neuroanatomical differences between dyslexic and control children, covering voxel-based morphometry, analyses of cortical thickness and surface, white matter tractography, morphometry of the planum temporale, and analyses of gyrification patterns. I will further discuss consistencies and inconsistencies between our results and previously published research, and future perspectives.